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Clot S

Diagnostic Kits

CRYOcheck™ Clot S™ is a clot-based assay intended for the quantitative determination of protein S activity in citrated human plasma. CRYOcheck Clot S initiates the common pathway of coagulation in plasma using a Russell’s viper venom (RVV-X) reagent to convert factor X to Xa in the presence of activated protein C, bypassing all factors above the common pathway.

  • Frozen format eliminates reconstitution errors
  • Unaffected by factor VIII:C levels up to 600%
  • Unaffected by unfractionated heparin or by low molecular weight heparin up to 1.0 IU/mL
  • Excellent linearity resulting in a broad reportable range
  • Up to 300 tests per kit when using 3.0 mL format

Clot S is used with C & S Diluent, available separately from Precision BioLogic.


Storage and Shelf Life


below -70°C




2 years after manufacturing date

Available Formats

Cat # Format

5 x 1.5 mL (PS Deficient)

5 x 1.5 mL (Activator)


5 x 3.0 mL (PS Deficient)

5 x 3.0 mL (Activator)

US, Canada, EU, and UK
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