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Clot C

Diagnostic Kits

CRYOcheck™ Clot C™ is a clot-based assay intended for the quantitative determination of protein C activity in citrated human plasma. CRYOcheck Clot C functions by direct activation of protein C in the patient sample using a protein C activator. The common pathway of coagulation is initiated with Russell’s viper venom (RVV-X) reagent to convert factor X to Xa, bypassing all factors above the common pathway.

  • Frozen format eliminates reconstitution errors
  • Unaffected by factor VIII:C activity levels up to 600%
  • Unaffected by samples from patients heterozygous for the factor V Leiden mutation
  • Interference by lupus anticoagulants has not been observed
  • Up to 300 tests per kit when using 3.0 mL format

CRYOcheck Clot C must be used with C & S Diluent, available separately from Precision BioLogic.


Storage and Shelf Life


below -70°C




2 years after manufacturing date

Available Formats

Cat # Format

5 x 1.5 mL (PC Deficient)

5 x 1.5 mL (Activator)


5 x 3.0 mL (PC Deficient)

5 x 3.0 mL (Activator)

US, Canada, EU, and UK
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